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Topwith Mouse support tagged Sci-fi (4,473 results)

Explore games with Mouse support tagged Sci-fi on itch.io. Science-fiction. Commonly including things like aliens, advanced technology, and settings of outer space or distant plan · Upload your games with Mouse support to itch.io to have them show up here.

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An Alternative Phase Invaders Story
Simulation
Gather unknown signals from deep, silent space
Simulation
Love is deception, germinated in desperation
Visual Novel
Try to survive and perhaps eventually even tame an unknown planet in this incremental semi-idle game.
Survival
Play in browser
A LGBT-friendly cozy sci-fi cooking/dating sim about making friends, finding love, and running a diner in deep space
Visual Novel
A semi-active, sci-fi themed incremental with elements of strategy and story.
Strategy
Play in browser
Alter genes, survive. Sci-fi RPG. 270k+
Interactive Fiction
Play in browser
Isometric insurgency simulator
Action
CAUTION: Escape from this supervillain at your own risk...
Visual Novel
CrossCode
$19.99
A retro-inspired 2D Action-RPG set in the distant future
Role Playing
Build spaceships and explore the cosmos
Simulation
Build a vast interstellar empire in 30 minutes flat.
Strategy
Play in browser
Tactical stealth meets top-down mecha combat and excessive destruction
Action
Movement Based Sword Fighting PVP
Action
Your blind date invades Earth!?
Visual Novel
Created a plant hybrid and he may want to kiss or eat you.
Visual Novel
Play in browser
Can you survive a hostile invasion from the planet Mars?
Survival
Roguelike auto-battler
Card Game
Play in browser
—Three different areas, three different decades, three different tales. A kinetic story anthology.
Visual Novel
A woman finally lives as herself.
Visual Novel
Fast-paced mecha themed third person shooter
Action
Fran Bow
$14.99
A young girl struggles with mental disorder and an unfair destiny.
Adventure
Chisel through a layer cake of thousand-year-old civilizations.
Freehold GamesVerified Account
Role Playing
"We've lived here for a long, long time."
Visual Novel
Play in browser
First-person, co-op horror game about capturing an alien.
Survival
An AI seedship must find a home for the last survivors of the human race
Strategy
Play in browser
An underwater Survival Horror Adventure - but what lies beyond the ocean's deepest depths?
Action
The conspiracy is no longer a theory.
Shooter
Mini city builder on a small planet for the Ludum Dare 38 Compo.
Simulation
Play in browser
The world is ending, and you are still paying rent. A future history.
Interactive Fiction
Play in browser
A sci fi hypnotic adventure with a mad scientist
Visual Novel
Play in browser
Travel through an overgrown megastructure.
Shooter
To get ahead in business, you need to Make Something of Yourself.
Visual Novel
A cyberpunk and solarpunk adventure-romance that explores a world where one side is forever day and the other, night.
Visual Novel
Jet-combat roguelite, occasionally with swords and 300+ other items to strap onto your jet.
Action
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